Foundayo Delivers up to 13% Weight Loss in Older Adults

Key Takeaways

• Adults 65+ lost up to 13% body weight at 72 weeks with Foundayo.
• Weight loss was dose-dependent, with the highest dose (17.2 mg) delivering the greatest reduction.
• Medicare Part D will cover Foundayo starting July 1, 2026 for $50/month.
• Foundayo is a once-daily oral GLP-1 pill taken any time without food or water restrictions.

What does the ATTAIN-1/2 analysis tell us about Foundayo weight loss in older adults?

Foundayo delivered up to 13% weight loss in older adults over 72 weeks. The ATTAIN-1/2 trials enrolled adults 65 and older with obesity or overweight, with and without type 2 diabetes. At the highest approved dose (17.2 mg), older adults in ATTAIN-1 lost an average of 13% of their body weight compared with only 1.6% on placebo (p < 0.001) (lilly.gcs-web.com). Lower doses produced smaller reductions: 7.9% at 5.5 mg and 11.3% at 9 mg versus placebo (pmc.ncbi.nlm.nih.gov). The weight loss pattern held in ATTAIN-2, which studied older adults with type 2 diabetes (pmc.ncbi.nlm.nih.gov).

How does Foundayo's administration differ from other GLP-1 meds?

Foundayo is a once-daily oral pill. You take it any time of day without planning around meals or water. Most other GLP-1 therapies require injections or strict timing around food. Foundayo removes those barriers (lilly.gcs-web.com).

What will Medicare beneficiaries pay for Foundayo starting July 1, 2026?

Medicare Part D patients who meet the Medicare GLP-1 Bridge clinical criteria will pay $50 per month for Foundayo starting July 1, 2026. The rate applies to new and existing users under the short-term demonstration program running through December 31, 2027 (lilly.gcs-web.com). Prior authorization may be required for the first fill, but refills don't need a new authorization unless you switch GLP-1 medications (foundayo.lilly.com).

FAQ

What is Foundayo weight loss potential for adults 65+?

ATTAIN-1 showed adults 65 and older lost up to 13% of body weight at 72 weeks on the 17.2 mg dose of Foundayo, compared with about 1.6% with placebo.

Is Foundayo a pill or injectable?

Foundayo is a once-daily oral GLP-1 pill that you can take any time of day, without food or water restrictions.

Will Medicare cover Foundayo?

Yes. Starting July 1, 2026, eligible Medicare Part D beneficiaries can get Foundayo under the GLP-1 Bridge program for a $50 monthly copay.

How long will Medicare cover Foundayo at that rate?

The $50 monthly copay under the Medicare GLP-1 Bridge program applies through December 31, 2027.

How does Foundayo compare to placebo in older adults?

In adults ≥65, placebo showed only 1.6% weight loss at 72 weeks, while Foundayo at 17.2 mg delivered 13%, making the drug highly effective compared to placebo.

This article is for general information and is not medical advice. GLP-1 medications are prescription drugs and fasting is not right for everyone — talk to a licensed healthcare provider before starting, stopping, or changing any treatment or eating pattern.